mouse EEF2K shRNA silencing AAV

Cat. No: shAAV-257788

Availability: Immediate

Name: AAV-m-EEF2K-shRNA

This is an AAV expressing shRNA for silencing of Mouse Eef2k.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Eef2k
Gene Name: eukaryotic elongation factor-2 kinase
Gene ID: 13631
Gene Synonyms: C86191; eEF-2K
ORF Size: 2175 bp
RefSeq#: NM_007908
Gene Description: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.
UniGene ID: Mm.361795