mouse EBF2 shRNA silencing AAV

Cat. No: shAAV-257707

Availability: 6-8 weeks

Name: AAV-m-EBF2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ebf2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ebf2
Gene Name: early B cell factor 2
Gene ID: 13592
Gene Synonyms: D14Ggc1e; EBF-2; Mmot1; O/E-3; OE-3
ORF Size: 1728 bp
RefSeq#: NM_010095
Gene Description: Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in turn regulates osteoclast differentiation. Acts in synergy with the Wnt-responsive LEF1/CTNNB1 pathway. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity).
UniGene ID: Mm.319947