mouse E2F4 shRNA silencing AAV

Cat. No: shAAV-257653

Availability: 4-5 weeks

Name: AAV-m-E2F4-shRNA

This is an AAV expressing shRNA for silencing of Mouse E2f4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: E2f4
Gene Name: E2F transcription factor 4
Gene ID: 104394
Gene Synonyms: 2010111M04Rik; AI427446
ORF Size: 1233 bp
RefSeq#: NM_148952
Gene Description: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-4 binds with high affinity to RBL1 and RBL2. In some instances, can also bind RB protein.
UniGene ID: Mm.34554