mouse DPH1 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-257409
Availability:
4-5 weeks
Name:
AAV-m-DPH1-shRNA
This is an AAV expressing shRNA for silencing of Mouse Dph1.
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Product Info
- Knockdown
- >70% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Dph1
- Gene Name
- diphthamide biosynthesis 1
- Gene ID
- 116905
- Gene Synonyms
- 2310011M22Rik; 4930488F09Rik; AW551873; Dph2l1; Ovca1
- ORF Size
- 1314 bp
- RefSeq#
- NM_144491
- Gene Description
- Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. When overexpressed, suppresses colony formation ability and growth rate of ovarian cancer cells. Acts also as a tumor suppressor in lung and breast cancers (By similarity). Plays a role in embryonic growth, organogenesis and postnatal survival (By similarity).
- UniGene ID
- Mm.41496
Related Products
Product | Cat No. |
---|---|
AAV-h-DPH1 | AAV-207273 |
AAV-m-DPH1 | AAV-257409 |
Ad-h-DPH1 | ADV-207273 |
Ad-m-DPH1 | ADV-257409 |
AAV-h-DPH1-shRNA | shAAV-207273 |
Ad-h-DPH1-shRNA | shADV-207273 |
Ad-m-DPH1-shRNA | shADV-257409 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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