mouse DOK7 shRNA silencing AAV

Cat. No: shAAV-257391

Availability: 6-8 weeks

Name: AAV-m-DOK7-shRNA

This is an AAV expressing shRNA for silencing of Mouse Dok7.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Dok7
Gene Name: docking protein 7
Gene ID: 231134
Gene Synonyms: A930013K19Rik; AW049091; Dok-7; EF-12; Oit5
ORF Size: 1404 bp
RefSeq#: NM_172708
Gene Description: Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.
UniGene ID: Mm.205483