mouse DNM1L shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-257348
Availability:
4-5 weeks
Name:
AAV-m-DNM1L-shRNA
This is an AAV expressing shRNA for silencing of Mouse Dnm1l.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Dnm1l
- Gene Name
- dynamin 1-like
- Gene ID
- 74006
- Gene Synonyms
- 6330417M19Rik; AI450666; Dlp1; Dnmlp1; Drp1; python
- ORF Size
- 1839 bp
- RefSeq#
- NM_152816
- Gene Description
- Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into ring-like structures which wrap around the scission site to constict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Required for normal brain development. Facilitates developmentally-regulated apoptosis during neural tube development. Required for a normal rate of cytochrome c release and caspase activation during apoptosis. Also required for mitochondrial fission during mitosis. May be involved in vesicle transport|Function: Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed.
- UniGene ID
- Mm.218820
Product Citations
This product is referenced in the following publications:
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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