mouse DMP1 shRNA silencing AAV

Cat. No: shAAV-257253

Availability: 6-8 weeks

Name: AAV-m-DMP1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Dmp1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Dmp1
Gene Name: dentin matrix protein 1
Gene ID: 13406
Gene Synonyms: AV020965; Dmp; PP
ORF Size: 1512 bp
RefSeq#: NM_016779
Gene Description: DMP1 may have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase it is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite.
UniGene ID: Mm.199008