mouse DERL3 shRNA silencing AAV

Cat. No: shAAV-257100

Availability: 6-8 weeks

Name: AAV-m-DERL3-shRNA

This is an AAV expressing shRNA for silencing of Mouse Derl3.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Derl3
Gene Name: Der1-like domain family, member 3
Gene ID: 70377
Gene Synonyms: 1810006I20Rik; 1810063P04Rik; derlin-3; IZP6
ORF Size: 687 bp
RefSeq#: NM_024440
Gene Description: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate.
UniGene ID: Mm.275878