mouse CTLA4 shRNA silencing AAV

Cat. No: shAAV-256310

Availability: 6-8 weeks

Name: AAV-m-CTLA4-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ctla4.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ctla4
Gene Name: cytotoxic T-lymphocyte-associated protein 4
Gene ID: 12477
Gene Synonyms: Cd152; Ctla-4; Ly-56
ORF Size: 672 bp
RefSeq#: NM_009843
Gene Description: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
UniGene ID: Mm.390