mouse CHL1 shRNA silencing AAV

Cat. No: shAAV-255405

Availability: 6-8 weeks

Name: AAV-m-CHL1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Chl1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Chl1
Gene Name: cell adhesion molecule L1-like
Gene ID: 12661
Gene Synonyms: A530023M13Rik; AI465420; CALL; LICAM2
ORF Size: 3630 bp
RefSeq#: NM_007697
Gene Description: Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane (By similarity).
UniGene ID: Mm.251288