mouse CDK5RAP2 shRNA silencing AAV

Cat. No: shAAV-255171

Availability: 4-5 weeks

Name: AAV-m-CDK5RAP2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Cdk5rap2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Cdk5rap2
Gene Name: CDK5 regulatory subunit associated protein 2
Gene ID: 214444
Gene Synonyms: 2900018K03Rik; an; mKIAA1633
ORF Size: 5469 bp
RefSeq#: NM_145990
Gene Description: Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in regulation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter. Together with MAPRE1, it may promote microtubule polymerization, bundle formation, growth and dynamics at the plus ends.
UniGene ID: Mm.379344