mouse CDC42BPB shRNA silencing AAV

Cat. No: shAAV-255097

Availability: 4-5 weeks

Name: AAV-m-CDC42BPB-shRNA

This is an AAV expressing shRNA for silencing of Mouse Cdc42bpb.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Cdc42bpb
Gene Name: CDC42 binding protein kinase beta
Gene ID: 217866
Gene Synonyms: MRCKb
ORF Size: 5142 bp
RefSeq#: NM_183016
Gene Description: Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A.
UniGene ID: Mm.27397