mouse CCR4 shRNA silencing AAV

Cat. No: shAAV-254903

Availability: 6-8 weeks

Name: AAV-m-CCR4-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ccr4.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ccr4
Gene Name: chemokine (C-C motif) receptor 4
Gene ID: 12773
Gene Synonyms: C-C CKR-4; CHEMR1; Cmkbr4; LESTR; Sdf1r
ORF Size: 1083 bp
RefSeq#: NM_009916
Gene Description: High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
UniGene ID: Mm.1337