mouse CBFA2T2 shRNA silencing AAV

Cat. No: shAAV-254594

Availability: 4-5 weeks

Name: AAV-m-CBFA2T2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Cbfa2t2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Cbfa2t2
Gene Name: core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)
Gene ID: 12396
Gene Synonyms: A430091M07; C330013D05Rik; Cbfa2t2h; MTGR1
ORF Size: 1785 bp
RefSeq#: NM_172860
Gene Description: CBFA2T2 may function as a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 which is produced in acute myeloid leukemia with the chromosomal translocation t(8;21). May thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth. May be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region.
UniGene ID: Mm.29914