mouse CAV2 shRNA silencing AAV

Cat. No: shAAV-254588

Availability: 4-5 weeks

Name: AAV-m-CAV2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Cav2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Cav2
Gene Name: caveolin 2
Gene ID: 12390
Gene Synonyms: AI447843
ORF Size: 489 bp
RefSeq#: NM_016900
Gene Description: CAV2 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).
UniGene ID: Mm.396075