mouse CANX shRNA silencing AAV

Cat. No: shAAV-254464

Availability: Immediate

Name: AAV-m-CANX-shRNA

This is an AAV expressing shRNA for silencing of Mouse Canx.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Canx
Gene Name: calnexin
Gene ID: 12330
Gene Synonyms: 1110069N15Rik; AI988026; Cnx; D11Ertd153e
ORF Size: 1776 bp
RefSeq#: NM_007597
Gene Description: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.
UniGene ID: Mm.248827