mouse CAMKK2 shRNA silencing AAV

Cat. No: shAAV-254451

Availability: 4-5 weeks

Name: AAV-m-CAMKK2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Camkk2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Camkk2
Gene Name: calcium/calmodulin-dependent protein kinase kinase 2, beta
Gene ID: 207565
Gene Synonyms: 6330570N16Rik; AW061083; mKIAA0787
ORF Size: 1626 bp
RefSeq#: NM_145358
Gene Description: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Seems to be involved in hippocampal activation of CREB1 (By similarity).
UniGene ID: Mm.394637