mouse BBC3 shRNA silencing AAV

Product Info

Knockdown

>60% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Recombinant AAV

AAV-ITR

AAV2

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Bbc3

Gene Name

BCL2 binding component 3

Gene ID

170770

Gene Synonyms

PUMA; PUMA/JFY1

ORF Size

582 bp

RefSeq#

NM_133234

Gene Description

Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Isoform 3 fails to show any growth-inhibitory or apoptotic activity|Function: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis.

UniGene ID

Mm.7660