mouse BACE1 shRNA silencing AAV

Cat. No: shAAV-253587

Availability: 4-5 weeks

Name: AAV-m-BACE1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Bace1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Bace1
Gene Name: beta-site APP cleaving enzyme 1
Gene ID: 23821
Gene Synonyms: ASP2; Bace; C76936
ORF Size: 1506 bp
RefSeq#: NM_011792
Gene Description: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
UniGene ID: Mm.24044