mouse ATP5E shRNA silencing AAV

Cat. No: shAAV-253296

Availability: 4-5 weeks

Name: AAV-m-ATP5E-shRNA

This is an AAV expressing shRNA for silencing of Mouse Atp5e.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Atp5e
Gene Name: ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
Gene ID: 67126
Gene Synonyms: 2410043G19Rik; ATPE; AV000645
ORF Size: 159 bp
RefSeq#: NM_025983
Gene Description: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits (By similarity).
UniGene ID: Mm.20841