mouse ATG7 shRNA silencing AAV

Cat. No: shAAV-253227

Availability: 4-5 weeks

Name: AAV-m-ATG7-shRNA

This is an AAV expressing shRNA for silencing of Mouse Atg7.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Atg7
Gene Name: autophagy related 7
Gene ID: 74244
Gene Synonyms: 1810013K23Rik; Agp7; Apg7l; Atg7l; Gm21553
ORF Size: 2097 bp
RefSeq#: NM_028835
Gene Description: Functions as an E1 enzyme essential for multisubstrates such as ATG8-like proteins and ATG12. Forms intermediate conjugates with ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). PE-conjugation to ATG8-like proteins is essential for autophagy. Also acts as an E1 enzyme for ATG12 conjugation to ATG5 and ATG3 (By similarity).
UniGene ID: Mm.275332