mouse ATG5 shRNA silencing AAV

Cat. No: shAAV-253226

Availability: Immediate

Name: AAV-m-ATG5-shRNA

This is an AAV expressing shRNA for silencing of Mouse Atg5.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Atg5
Gene Name: autophagy related 5
Gene ID: 11793
Gene Synonyms: 2010107M05Rik; 3110067M24Rik; Apg5l; Atg5l; AW319544; C88337; Paddy
ORF Size: 828 bp
RefSeq#: NM_053069
Gene Description: Required for autophagy. Conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed (By similarity)|Function: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
UniGene ID: Mm.22264