mouse ATG4D shRNA silencing AAV

Cat. No: shAAV-253224

Availability: 4-5 weeks

Name: AAV-m-ATG4D-shRNA

This is an AAV expressing shRNA for silencing of Mouse Atg4d.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Atg4d
Gene Name: autophagy related 4D, cysteine peptidase
Gene ID: 235040
Gene Synonyms: 9830134P12Rik; APG4-D; Apg4d; Atg4dl; Autl4
ORF Size: 1425 bp
RefSeq#: NM_153583
Gene Description: Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
UniGene ID: Mm.440165