mouse ASF1A shRNA silencing AAV

Cat. No: shAAV-253150

Availability: 4-5 weeks

Name: AAV-m-ASF1A-shRNA

This is an AAV expressing shRNA for silencing of Mouse Asf1a.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Asf1a
Gene Name: anti-silencing function 1A histone chaperone
Gene ID: 66403
Gene Synonyms: 2310079C17Rik; C79052
ORF Size: 615 bp
RefSeq#: NM_025541
Gene Description: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
UniGene ID: Mm.272989