mouse ARHGEF7 shRNA silencing AAV

Cat. No: shAAV-252981

Availability: 4-5 weeks

Name: AAV-m-ARHGEF7-shRNA

This is an AAV expressing shRNA for silencing of Mouse Arhgef7.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Arhgef7
Gene Name: Rho guanine nucleotide exchange factor (GEF7)
Gene ID: 54126
Gene Synonyms: betaPix; betaPix-b; betaPix-c; Cool; cool-1; mKIAA0142; p85Cool1; p85SPR; Pak3bp; PIX
ORF Size: 1941 bp
RefSeq#: NM_017402
Gene Description: Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
UniGene ID: Mm.244068