mouse ARC shRNA silencing AAV

Cat. No: shAAV-252890

Availability: 6-8 weeks

Name: AAV-m-ARC-shRNA

This is an AAV expressing shRNA for silencing of Mouse Arc.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Arc
Gene Name: activity regulated cytoskeletal-associated protein
Gene ID: 11838
Gene Synonyms: Arc3.1; arg3.1; C86064; mArc
ORF Size: 1191 bp
RefSeq#: NM_018790
Gene Description: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration.
UniGene ID: Mm.25405