mouse AQR shRNA silencing AAV

Cat. No: shAAV-252884

Availability: 4-5 weeks

Name: AAV-m-AQR-shRNA

This is an AAV expressing shRNA for silencing of Mouse Aqr.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Aqr
Gene Name: aquarius
Gene ID: 11834
Gene Synonyms: AW495846; mKIAA0560
ORF Size: 4446 bp
RefSeq#: NM_009702
Gene Description: Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
UniGene ID: Mm.2545