mouse APOA5 shRNA silencing AAV

Cat. No: shAAV-252832

Availability: 6-8 weeks

Name: AAV-m-APOA5-shRNA

This is an AAV expressing shRNA for silencing of Mouse Apoa5.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Apoa5
Gene Name: apolipoprotein A-V
Gene ID: 66113
Gene Synonyms: 1300007O05Rik; Apoav; RAP3
ORF Size: 1107 bp
RefSeq#: NM_080434
Gene Description: Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) (By similarity). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages.
UniGene ID: Mm.29738