mouse AMOT shRNA silencing AAV

Cat. No: shAAV-252577

Availability: 4-5 weeks

Name: AAV-m-AMOT-shRNA

This is an AAV expressing shRNA for silencing of Mouse Amot.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Amot
Gene Name: angiomotin
Gene ID: 27494
Gene Synonyms: CAG-2; D0Kist1; Sii6
ORF Size: 1863 bp
RefSeq#: NM_153319
Gene Description: Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.
UniGene ID: Mm.100068