mouse ACE2 shRNA silencing AAV

Cat. No: shAAV-251906

Availability: 6-8 weeks

Name: AAV-m-ACE2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ace2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ace2
Gene Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
Gene ID: 70008
Gene Synonyms: 2010305L05Rik
ORF Size: 2418 bp
RefSeq#: NM_027286
Gene Description: Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
UniGene ID: Mm.13451