mouse ABI2 shRNA silencing AAV

Cat. No: shAAV-251828

Availability: 4-5 weeks

Name: AAV-m-ABI2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Abi2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Abi2
Gene Name: abl-interactor 2
Gene ID: 329165
Gene Synonyms: 8430425M24Rik; AI839867; C130078H13
ORF Size: 1341 bp
RefSeq#: NM_198127
Gene Description: ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA.
UniGene ID: Mm.212066