mouse AADACL1 shRNA silencing AAV

Cat. No: shAAV-251729

Availability: 6-8 weeks

Name: AAV-m-AADACL1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Nceh1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Nceh1
Gene Name: neutral cholesterol ester hydrolase 1
Gene ID: 320024
Gene Synonyms: Aadacl1; B230106I24Rik; CPO-BP; Nceh
ORF Size: 1227 bp
RefSeq#: NM_178772
Gene Description: Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration.
UniGene ID: Mm.24576