mouse 4921515J06RIK shRNA silencing AAV

Cat. No: shAAV-251013

Availability: 6-8 weeks

Name: AAV-m-4921515J06RIK-shRNA

This is an AAV expressing shRNA for silencing of Mouse Henmt1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Henmt1
Gene Name: HEN1 methyltransferase homolog 1 (Arabidopsis)
Gene ID: 66715
Gene Synonyms: 4921515J06Rik; Hen1; mHEN1
ORF Size: 1188 bp
RefSeq#: NM_025723
Gene Description: Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis (By similarity).
UniGene ID: Mm.158124