mouse SYNE3 shRNA silencing AAV

Cat. No: shAAV-250976

Availability: 6-8 weeks

Name: AAV-m-SYNE3-shRNA

This is an AAV expressing shRNA for silencing of Mouse Syne3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Syne3
Gene Name: spectrin repeat containing, nuclear envelope family member 3
Gene ID: 212073
Gene Synonyms: nesprin-3
ORF Size: 2928 bp
RefSeq#: NM_172500
Gene Description: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.
UniGene ID: Mm.212688