mouse 2610109H07RIK shRNA silencing AAV

Cat. No: shAAV-250804

Availability: 6-8 weeks

Name: AAV-m-2610109H07RIK-shRNA

This is an AAV expressing shRNA for silencing of Mouse Draxin.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Draxin
Gene Name: dorsal inhibitory axon guidance protein
Gene ID: 70433
Gene Synonyms: 2610109H07Rik; neucrin
ORF Size: 1032 bp
RefSeq#: NM_027426
Gene Description: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway (By similarity).
UniGene ID: Mm.275288