mouse MEAF6 shRNA silencing AAV

Cat. No: shAAV-250622

Availability: 6-8 weeks

Name: AAV-m-MEAF6-shRNA

This is an AAV expressing shRNA for silencing of Mouse Meaf6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Meaf6
Gene Name: MYST/Esa1-associated factor 6
Gene ID: 70088
Gene Synonyms: 2310005N01Rik; 2810036M01Rik
ORF Size: 576 bp
RefSeq#: NM_027310
Gene Description: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
UniGene ID: Mm.291214