mouse 1500010J02RIK shRNA silencing AAV

Cat. No: shAAV-250206

Availability: 6-8 weeks

Name: AAV-m-1500010J02RIK-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ctc1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ctc1
Gene Name: CTS telomere maintenance complex component 1
Gene ID: 68964
Gene Synonyms: 1500010J02Rik; AAF-132; AAF132
ORF Size: 3639 bp
RefSeq#: NM_001143790
Gene Description: Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
UniGene ID: Mm.477845