human INTS10 shRNA silencing AAV

Cat. No: shAAV-234475

Availability: 6-8 weeks

Name: AAV-h-INTS10-shRNA

This is an AAV expressing shRNA for silencing of Human INTS10.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: INTS10
Gene Name: integrator complex subunit 10
Gene ID: 55174
Gene Synonyms: C8orf35; INT10
ORF Size: 1901 bp
RefSeq#: NM_018142
Gene Description: INTS10 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)).(supplied by OMIM, Mar 2008)
HGNC ID: HGNC:25548