human SLC30A8 shRNA silencing AAV

Cat. No: shAAV-234269

Availability: 6-8 weeks

Name: AAV-h-SLC30A8-shRNA

This is an AAV expressing shRNA for silencing of Human SLC30A8.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SLC30A8
Gene Name: solute carrier family 30 member 8
Gene ID: 169026
Gene Synonyms: ZnT-8; ZNT8
ORF Size: 963 bp
RefSeq#: NM_173851
Gene Description: SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.
HGNC ID: HGNC:20303