human ATP6V0E2 shRNA silencing AAV

Cat. No: shAAV-234179

Availability: 6-8 weeks

Name: AAV-h-ATP6V0E2-shRNA

This is an AAV expressing shRNA for silencing of Human ATP6V0E2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ATP6V0E2
Gene Name: ATPase H+ transporting V0 subunit e2
Gene ID: 155066
Gene Synonyms: ATP6V0E2L; C7orf32
ORF Size: 642 bp
RefSeq#: NM_145230
Gene Description: Multisubunit vacuolar-type proton pumps, or H(+)-ATPases, acidify various intracellular compartments, such as vacuoles, clathrin-coated and synaptic vesicles, endosomes, lysosomes, and chromaffin granules. H(+)-ATPases are also found in plasma membranes of specialized cells, where they play roles in urinary acidification, bone resorption, and sperm maturation. Multiple subunits form H(+)-ATPases, with proteins of the V1 class hydrolyzing ATP for energy to transport H+, and proteins of the V0 class forming an integral membrane domain through which H+ is transported. ATP6V0E2 encodes an isoform of the H(+)-ATPase V0 e subunit, an essential proton pump component (Blake-Palmer et al., 2007 (PubMed 17350184)).(supplied by OMIM, Mar 2008)
HGNC ID: HGNC:21723