human CLDN4 shRNA silencing AAV

Cat. No: shAAV-231624

Availability: 6-8 weeks

Name: AAV-h-CLDN4-shRNA

This is an AAV expressing shRNA for silencing of Human CLDN4.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CLDN4
Gene Name: claudin 4
Gene ID: 1364
Gene Synonyms: CPE-R; CPER; CPETR; CPETR1; hCPE-R; WBSCR8
ORF Size: 630 bp
RefSeq#: NM_001305
Gene Description: CLDN4 encodes an integral membrane protein, which belongs to the claudin family. The protein is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. CLDN4 is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
UniGene ID: Hs.699253
HGNC ID: HGNC:2046