human DDX18 shRNA silencing AAV

Cat. No: shAAV-230166

Availability: 4-5 weeks

Name: AAV-h-DDX18-shRNA

This is an AAV expressing shRNA for silencing of Human DDX18.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DDX18
Gene Name: DEAD-box helicase 18
Gene ID: 8886
Gene Synonyms: MrDb
ORF Size: 2013 bp
RefSeq#: NM_006773
Gene Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it is activated by Myc protein.
UniGene ID: Hs.363492
HGNC ID: HGNC:2741