human HPGD shRNA silencing AAV

Cat. No: shAAV-230151

Availability: 6-8 weeks

Name: AAV-h-HPGD-shRNA

This is an AAV expressing shRNA for silencing of Human HPGD.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HPGD
Gene Name: hydroxyprostaglandin dehydrogenase 15-(NAD)
Gene ID: 3248
Gene Synonyms: 15-PGDH; PGDH; PGDH1; PHOAR1; SDR36C1
ORF Size: 801 bp
RefSeq#: NM_000860
Gene Description: HPGD encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.596913
HGNC ID: HGNC:5154