human PDE7A shRNA silencing AAV

Cat. No: shAAV-229335

Availability: 6-8 weeks

Name: AAV-h-PDE7A-shRNA

This is an AAV expressing shRNA for silencing of Human PDE7A.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PDE7A
Gene Name: phosphodiesterase 7A
Gene ID: 5150
Gene Synonyms: HCP1; PDE7
ORF Size: 1371 bp
RefSeq#: NM_002603
Gene Description: PDE7A belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
UniGene ID: Hs.527119
HGNC ID: HGNC:8791