human CPE shRNA silencing AAV

Cat. No: shAAV-229236

Availability: 4-5 weeks

Name: AAV-h-CPE-shRNA

This is an AAV expressing shRNA for silencing of Human CPE.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CPE
Gene Name: carboxypeptidase E
Gene ID: 1363
Gene Synonyms: CPH
ORF Size: 1431 bp
RefSeq#: NM_001873
Gene Description: CPE encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.
UniGene ID: Hs.75360
HGNC ID: HGNC:2303