human YWHAG shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-228004
Availability:
4-5 weeks
Name:
AAV-h-YWHAG-shRNA
This is an AAV expressing shRNA for silencing of Human YWHAG.
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Product Info
- Knockdown
- >50% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- YWHAG
- Gene Name
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
- Gene ID
- 7532
- Gene Synonyms
- 14-3-3GAMMA; PPP1R170
- ORF Size
- 744 bp
- RefSeq#
- NM_012479
- Gene Description
- YWHAG product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.
- UniGene ID
- Hs.520974
- HGNC ID
- HGNC:12852
Related Products
Product | Cat No. |
---|---|
AAV-h-YWHAG | AAV-228004 |
AAV-m-YWHAG | AAV-276489 |
Ad-h-YWHAG | ADV-228004 |
Ad-m-YWHAG | ADV-276489 |
AAV-m-YWHAG-shRNA | shAAV-276489 |
Ad-h-YWHAG-shRNA | shADV-228004 |
Ad-m-YWHAG-shRNA | shADV-276489 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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