human YME1L1 shRNA silencing AAV

Cat. No: shAAV-227979

Availability: 4-5 weeks

Name: AAV-h-YME1L1-shRNA

This is an AAV expressing shRNA for silencing of Human YME1L1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: YME1L1
Gene Name: YME1 like 1 ATPase
Gene ID: 10730
Gene Synonyms: FTSH; MEG4; PAMP; YME1L
ORF Size: 2151 bp
RefSeq#: NM_014263
Gene Description: YME1L1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.499145
HGNC ID: HGNC:12843