human XRN2 shRNA silencing AAV

Cat. No: shAAV-227938

Availability: 4-5 weeks

Name: AAV-h-XRN2-shRNA

This is an AAV expressing shRNA for silencing of Human XRN2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: XRN2
Gene Name: 5'-3' exoribonuclease 2
Gene ID: 22803
ORF Size: 2853 bp
RefSeq#: NM_012255
Gene Description: XRN2 shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for this gene; however, their full-length nature is not known.
UniGene ID: Hs.255932
HGNC ID: HGNC:12836