human XCR1 shRNA silencing AAV

Cat. No: shAAV-227876

Availability: 6-8 weeks

Name: AAV-h-XCR1-shRNA

This is an AAV expressing shRNA for silencing of Human XCR1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: XCR1
Gene Name: X-C motif chemokine receptor 1
Gene ID: 2829
Gene Synonyms: CCXCR1; GPR5
ORF Size: 1002 bp
RefSeq#: NM_005283
Gene Description: XCR1 is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
UniGene ID: Hs.248116
HGNC ID: HGNC:1625