human WDR4 shRNA silencing AAV

Cat. No: shAAV-227672

Availability: 4-5 weeks

Name: AAV-h-WDR4-shRNA

This is an AAV expressing shRNA for silencing of Human WDR4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: WDR4
Gene Name: WD repeat domain 4
Gene ID: 10785
Gene Synonyms: TRM82; TRMT82
ORF Size: 801 bp
RefSeq#: NM_018669
Gene Description: WDR4 encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WDR4 is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternatively spliced transcript variants have been found for this gene.
UniGene ID: Hs.248815
HGNC ID: HGNC:12756